Viral transformation of epithelial cells.

  title={Viral transformation of epithelial cells.},
  author={Jennifer A. Regan and Laimonis Laimins},
  journal={Methods in molecular biology},
Approximately 18% of human cancers have a viral etiology and the majority of these involve transformation of epithelial cells. Viral proteins transform epithelia by inducing alterations in the normal cell growth and differentiation pathways through the targeting of host proteins. Among the DNA viruses responsible for causing carcinomas are the human papillomaviruses as well as several members of the herpes and polyomavirus families. A number of techniques have been developed to study the… CONTINUE READING