Viral suppression in HIV studies: combining times to suppression and rebound.

Abstract

In HIV-1 clinical trials the interest is often to compare how well treatments suppress the HIV-1 RNA viral load. The current practice in statistical analysis of such trials is to define a single ad hoc composite event which combines information about both the viral load suppression and the subsequent viral rebound, and then analyze the data using standard… (More)
DOI: 10.1111/biom.12140

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