Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever.

@article{Myster2015ViralSI,
  title={Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever.},
  author={Françoise Myster and Leonor Palmeira and Oc{\'e}ane Sorel and Fabrice Bouillenne and Edwin Depauw and Isabelle Schwartz-Cornil and Alain F C Vanderplasschen and Benjamin G Dewals},
  journal={Journal of virology},
  year={2015},
  volume={89 7},
  pages={3630-47}
}
UNLABELLED Viral semaphorins are semaphorin 7A (sema7A) mimics found in pox- and herpesviruses. Among herpesviruses, semaphorins are encoded by gammaherpesviruses of the Macavirus genus only. Alcelaphine herpesvirus 1 (AlHV-1) is a macavirus that persistently infects wildebeest asymptomatically but induces malignant catarrhal fever (MCF) when transmitted to several species of susceptible ruminants and the rabbit model. MCF is caused by the activation/proliferation of latently infected T… CONTINUE READING