Viral proteins required for the in vitro replication of vesicular stomatitis virus defective interfering particle genome RNA.

@article{Peluso1988ViralPR,
  title={Viral proteins required for the in vitro replication of vesicular stomatitis virus defective interfering particle genome RNA.},
  author={Richard W. Peluso and Sue A. Moyer},
  journal={Virology},
  year={1988},
  volume={162 2},
  pages={369-76}
}
The viral proteins required for VSV RNA replication have been partially purified. With the use of monoclonal antibodies specific for the VSV N protein we have identified a putative N/NS complex present in the soluble protein fraction of infected cells. The complex is stable upon partial purification, contains the N and NS proteins in a 1:1 molar ratio, and has an elongated shape based on its hydrodynamic properties. Depletion of the N/NS complex from the infected cell soluble protein fraction… CONTINUE READING

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