Viral mechanisms of adipose dysfunction: lessons from HIV-1 Vpr.

@article{Agarwal2015ViralMO,
  title={Viral mechanisms of adipose dysfunction: lessons from HIV-1 Vpr.},
  author={Neeti Agarwal and Ashok Balasubramanyam},
  journal={Adipocyte},
  year={2015},
  volume={4 1},
  pages={
          55-9
        }
}
HIV-associated lipodystrophy is a heterogeneous, evolving condition associated with fundamental defects in adipose tissue differentiation, turnover and function. Although many antiretroviral drugs can affect adipose tissues adversely, clinical evidence suggests that factors associated with the virus per se could play a role. We have focused on the possibility that an HIV accessory protein, viral protein R (Vpr) could dysregulate metabolically critical transcription factors to cause the adipose… CONTINUE READING

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  • 2017
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References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES