Viral load as a predictor of the risk of cervical intraepithelial neoplasia.

@article{Schlecht2003ViralLA,
  title={Viral load as a predictor of the risk of cervical intraepithelial neoplasia.},
  author={Nicolas F. Schlecht and Andrea Trevisan and Eliane Duarte-Franco and Thomas Rohan and Alex S Ferenczy and Luisa L. Villa and Eduardo L Franco},
  journal={International journal of cancer},
  year={2003},
  volume={103 4},
  pages={519-24}
}
HPV infections are believed to be a necessary cause of cervical cancer. Viral burden, as a surrogate indicator for persistence, may help predict risk of subsequent SIL. We used results of HPV test and cytology data repeated every 4-6 months in 2,081 women participating in a longitudinal study of the natural history of HPV infection and cervical neoplasia in São Paulo, Brazil. Using the MY09/11 PCR protocol, 473 women were positive for HPV DNA during the first 2 visits. We retested all positive… CONTINUE READING