Viral load and disease progression as responsible for endothelial activation and/or injury in human immunodeficiency virus-1-infected patients.

@article{Larraaga2003ViralLA,
  title={Viral load and disease progression as responsible for endothelial activation and/or injury in human immunodeficiency virus-1-infected patients.},
  author={Gabriela de Larra{\~n}aga and Alejandro Petroni and Gabriel Deluchi and Beatriz Sanz Alonso and Jorge A. Benetucci},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2003},
  volume={14 1},
  pages={
          15-8
        }
}
The endothelium participates in haemostasis, inflammation, blood pressure regulation and other physiological systems. Consequently, endothelial dysfunction has been related to hypertension, thrombosis and atherosclerosis. Both von Willebrand factor (vWF) and tissue-type plasminogen activator (t-PA) are synthesized by the endothelium and their plasma levels increased during endothelium activation or injury. So far, they are well-known markers of endothelial cell function. Many circumstances… CONTINUE READING
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