Viral interaction with the host cell sumoylation system.

  title={Viral interaction with the host cell sumoylation system.},
  author={Van G. Wilson and Dandapani Rangasamy},
  journal={Virus research},
  volume={81 1-2},
A novel host cell post-translational modification system termed sumoylation was discovered recently. Sumoylation is an enzymatic process that is biochemically analogous to, but functionally distinct from ubiquitinylation. As in ubiquitinylation, sumoylation involves the attachment of a small protein moiety, SUMO, to substrate proteins. Conjugation of SUMO does not typically lead to degradation of the substrate and instead causes functional alterations or changes in intracellular localization… CONTINUE READING


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