Viral infections in mice with reconstituted human immune system components.

@article{Mnz2014ViralII,
  title={Viral infections in mice with reconstituted human immune system components.},
  author={Christian M{\"u}nz},
  journal={Immunology letters},
  year={2014},
  volume={161 1},
  pages={
          118-24
        }
}
Pathogenic viruses are often difficult to study due to their exclusive tropism for humans. The development of mice with human immune system components opens the possibility to study those human pathogens with a tropism for the human hematopoietic lineage in vivo. These include HCMV, EBV, KSHV, HIV, HTLV-1, dengue virus and JC virus. Furthermore, some human pathogens, like HSV-2, adenovirus, HCV, HBV and influenza A virus, with an additional tropism for somatic mouse tissues or for additional… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 87 REFERENCES

HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors.

  • Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
  • 2014

Humanized-BLT mouse model of Kaposi's sarcoma-associated herpesvirus infection.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2014