Viral infection and the pathogenesis of dilated cardiomyopathy.

  title={Viral infection and the pathogenesis of dilated cardiomyopathy.},
  author={Tami A. Martino and Peter J Y Liu and Michael Sole},
  journal={Circulation research},
  volume={74 2},
Long-term follow-up studies of patients with suspected viral myocarditis reveal progression to dilated cardiomyopathy (DCM) in a significant number of cases. Thus, an underlying viral etiology has been hypothesized in the pathogenesis of ongoing heart disease that leads to DCM. Recent application of molecular biology in clinical diagnosis has strengthened this hypothesis. By use of probe hybridization and polymerase chain reaction, enteroviral RNA has been detected in the myocardium of patients… CONTINUE READING
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