Viral-induced systemic necrosis in plants involves both programmed cell death and the inhibition of viral multiplication, which are regulated by independent pathways.

@article{Komatsu2010ViralinducedSN,
  title={Viral-induced systemic necrosis in plants involves both programmed cell death and the inhibition of viral multiplication, which are regulated by independent pathways.},
  author={K. Komatsu and M. Hashimoto and J. Ozeki and Y. Yamaji and K. Maejima and H. Senshu and M. Himeno and Yukari Okano and S. Kagiwada and S. Namba},
  journal={Molecular plant-microbe interactions : MPMI},
  year={2010},
  volume={23 3},
  pages={
          283-93
        }
}
Resistant plants respond rapidly to invading avirulent plant viruses by triggering a hypersensitive response (HR). An HR is accompanied by a restraint of virus multiplication and programmed cell death (PCD), both of which have been observed in systemic necrosis triggered by a successful viral infection. Here, we analyzed signaling pathways underlying the HR in resistance genotype plants and those leading to systemic necrosis. We show that systemic necrosis in Nicotiana benthamiana, induced by… Expand
Identification of MAPKs as signal transduction components required for the cell death response during compatible infection by the synergistic pair Potato virus X-Potato virus Y.
TLDR
It is demonstrated that SipK, WIPK, MEK1 and MKK1 function as positive regulators of PVX-PVY-induced cell death, which partially compromised the HR-like response induced by the synergistic interaction of Potato virus X with Potato virus Y. Expand
Studies on molecular mechanisms underlying virus-induced systemic necrosis associated with host defense responses
  • K. Komatsu
  • Biology
  • Journal of General Plant Pathology
  • 2013
TLDR
The systemic necrosis induced by infection with a potexvirus, Plantago asiatica mosaic virus (PlAMV), in the experimental host Nicotiana benthamiana was analyzed using a virus-induced gene silencing (VIGS) approach and it was revealed that host factors required for HR induction are also involved in the induction of the systemic Necrosis. Expand
Oxylipin Biosynthesis Genes Positively Regulate Programmed Cell Death during Compatible Infections with the Synergistic Pair Potato Virus X-Potato Virus Y and Tomato Spotted Wilt Virus
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It is concluded that oxylipin metabolism is a critical component that positively regulates the process of PCD during compatible plant-virus interactions but does not play a role in restraining virus accumulation in planta. Expand
A necrosis-inducing elicitor domain encoded by both symptomatic and asymptomatic Plantago asiatica mosaic virus isolates, whose expression is modulated by virus replication.
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The data suggest that necrotic symptoms induced by PlAMV infection depend on the accumulation of a non-isolate specific elicitor HEL (even from nonnecrosis isolates), whose expression is indirectly regulated by amino acid 1,154 that controls replication. Expand
Cell death triggered by the P25 protein in Potato virus X-associated synergisms results from endoplasmic reticulum stress in Nicotiana benthamiana.
The synergistic interaction of Potato virus X (PVX) with a number of potyviruses results in systemic necrosis in Nicotiana spp. Previous investigations have indicated that the viral suppressor of RNAExpand
Cell Death Is Not Sufficient for the Restriction of Potato Virus Y Spread in Hypersensitive Response-Conferred Resistance in Potato
TLDR
It is proposed that HR should be regarded as a process where the dynamics of events is crucial for effectiveness of viral arrest albeit the exact mechanism conferring this resistance remains unknown. Expand
Comparative analysis of transcriptomic and hormonal responses to compatible and incompatible plant-virus interactions that lead to cell death.
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It is shown that SN induced by a PVX recombinant virus expressing a potyviral helper component-proteinase (HC-Pro) gene is associated with PCD, and a potential contribution of proteasome dysfunction to the increased pathogenicity observed in PVX-Potyvirus mixed infections. Expand
Programmed cell death pathways induced by early plant-virus infection are determined by isolate virulence and stage of infection
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Findings highlight how quantification of dead cell deformation and electrolyte leakage offer a new understanding of compatible and incompatible plant responses to early virus infection in plants. Expand
Tomato plant cell death induced by inhibition of HSP90 is alleviated by Tomato yellow leaf curl virus infection.
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It is shown that the chaperone HSP90 and its co-chaperone SGT1 (suppressor of the G2 allele of Skp1) are involved in the establishment of TYLCV infection, which leads to the accumulation of damaged ubiquitinated proteins and to a cell death phenotype. Expand
Is modulating virus virulence by induced systemic resistance realistic?
  • F. Faoro, F. Gozzo
  • Biology, Medicine
  • Plant science : an international journal of experimental plant biology
  • 2015
TLDR
ISR induction, has proved to be a promising strategy to control virus disease, particularly by seed bacterization with a mixture of plant growth-promoting rhizobacteria, however, the use of any of these treatments should be integrated with cultivation practices that reduce vector pressure by theUse of insecticides, or by Bt crops. Expand
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