Viral hepatitis and liver cancer: the case of hepatitis C

  title={Viral hepatitis and liver cancer: the case of hepatitis C},
  author={Massimo Levrero},
Chronic infection with the hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC) worldwide. The pathogenesis of HCC in HCV infection has extensively been analysed. Hepatitis C virus-induced chronic inflammation and the effects of cytokines in the development of fibrosis and liver cell proliferation are considered as one of the major pathogenic mechanisms. Increasing experimental evidence suggests that HCV contributes to HCC by directly modulating… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 182 extracted citations

Hepatitis C Virus

View 5 Excerpts
Highly Influenced

Hepatitis C virus-induced hepatocarcinogenesis.

Journal of hepatology • 2009
View 8 Excerpts
Highly Influenced

Natural Antimicrobial Agents

Sustainable Development and Biodiversity • 2018


Publications referenced by this paper.
Showing 1-10 of 44 references

Molecular Pathogenesis

D Moradpour, Wands
View 3 Excerpts
Highly Influenced

Hepatology 42: 809–818

Nelson DR, Gonzalez-Peralta RP, Qian K, Xu Y, Marousis • 2005

J Virol 79: 7648–7657

Christman JW.
Jordan R, Wang L, Graczyk TM, Block TM, Romano PR. • 2005

Oncogene 24: 6119–6132

O Hermine
Perlemuter G, Sabile A, Letteron P, Vona G, Topilco A, • 2005

Gastroenterology 126: 102–110

A Crax
Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, • 2004

Gastroenterology 126: 529–540

Blight KJ, Kolykhalov AA, Rice CM. (2000). Science 290: • 2004

Gastroenterology 126: 859–872

EJ Kremer
El-Serag HB, Davila JA, Petersen NJ, McGlynn KA. (2003). • 2004

Ricerca sul Cancro (AIRC), from the ‘Ministero dell’Istruzione dell’Università e della Ricerca Scientifica’ (PRIN, FIRB) and from the European Community (LSHCCT-2004-503576)

per la
View 1 Excerpt

Cancer 97: 3036–3043

K Yanagi
Okabe H, Satoh S, Kato T, Kitahara O, Yanagawa R, • 2003

Cancer Res 63: 5021–5027

Foy E, Li K, Wang C, Sumpter Jr R, Ikeda M, Lemon SM • 2003

Similar Papers

Loading similar papers…