Viral hepatitis and liver cancer: the case of hepatitis C

@article{Levrero2006ViralHA,
  title={Viral hepatitis and liver cancer: the case of hepatitis C},
  author={Massimo Levrero},
  journal={Oncogene},
  year={2006},
  volume={25},
  pages={3834-3847}
}
Chronic infection with the hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC) worldwide. The pathogenesis of HCC in HCV infection has extensively been analysed. Hepatitis C virus-induced chronic inflammation and the effects of cytokines in the development of fibrosis and liver cell proliferation are considered as one of the major pathogenic mechanisms. Increasing experimental evidence suggests that HCV contributes to HCC by directly modulating… CONTINUE READING
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