Viral hepatitis: Cell-culture-derived HCV—a promising vaccine antigen

@article{Gottwein2013ViralHC,
  title={Viral hepatitis: Cell-culture-derived HCV—a promising vaccine antigen},
  author={Judith Margarete Gottwein and Jens Bukh},
  journal={Nature Reviews Gastroenterology &Hepatology},
  year={2013},
  volume={10},
  pages={508-509}
}
With millions of humans infected yearly with HCV, leading to cirrhosis and cancer, a vaccine is urgently needed. Cultured virus particles constitute the antigen in most antiviral vaccines. A study in mice demonstrated induction of neutralizing antibodies by immunization with cell-culture-derived HCV, providing new possibilities for vaccine development. 
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