Viral genomic single-stranded RNA directs the pathway toward a T=3 capsid.

@article{Basnak2010ViralGS,
  title={Viral genomic single-stranded RNA directs the pathway toward a T=3 capsid.},
  author={Gabriella Basnak and Victoria L Morton and Ottar Rolfsson and Nicola J Stonehouse and Alison E Ashcroft and Peter G. Stockley},
  journal={Journal of molecular biology},
  year={2010},
  volume={395 5},
  pages={
          924-36
        }
}
The molecular mechanisms controlling genome packaging by single-stranded RNA viruses are still largely unknown. It is necessary in most cases for the protein to adopt different conformations at different positions on the capsid lattice in order to form a viral capsid from multiple copies of a single protein. We showed previously that such quasi-equivalent conformers of RNA bacteriophage MS2 coat protein dimers (CP(2)) can be switched by sequence-specific interaction with a short RNA stem-loop… CONTINUE READING
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