Viral exploitation of actin: force-generation and scaffolding functions in viral infection

@article{Spear2014ViralEO,
  title={Viral exploitation of actin: force-generation and scaffolding functions in viral infection},
  author={Mark Spear and Yuntao Wu},
  journal={Virologica Sinica},
  year={2014},
  volume={29},
  pages={139-147}
}
As a fundamental component of the host cellular cytoskeleton, actin is routinely engaged by infecting viruses. Furthermore, viruses from diverse groups, and infecting diverse hosts, have convergently evolved an array of mechanisms for manipulating the actin cytoskeleton for efficacious infection. An ongoing chorus of research now indicates that the actin cytoskeleton is critical for viral replication at many stages of the viral life cycle, including binding, entry, nuclear localization, genomic… CONTINUE READING

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