Viral encephalitis: familiar infections and emerging pathogens

@article{Whitley2002ViralEF,
  title={Viral encephalitis: familiar infections and emerging pathogens},
  author={Richard J Whitley and John W. Gnann},
  journal={The Lancet},
  year={2002},
  volume={359},
  pages={507-513}
}

Viral encephalitis

It is essential to commence early treatment with intravenous acyclovir in patients suspected of having HSE because of the remarkable safety and efficacy of this drug and the dangers of delaying potentially effective treatment of life threatening disease.

Recent issues in herpes simplex encephalitis

Some of the recently published management guidelines for HSE are considered and comment on various current issues of contention, including the timing and frequency of cerebrospinal fluid examinations for the polymerase chain reaction detection of HSV, decisions regarding acyclovir therapy including the consequences of delay in its initiation, and the use of corticosteroids in the disease.

Virus-Induced Encephalitis and Innate Immune Responses – A Focus on Emerging or Re-Emerging Viruses

Interestingly, CHIKV-associated neuropathology was first described in the 1960s but it is the unprecedented incidence rate in the Indian Ocean with efficient clinical facilities that allowed a better description of cases with severe encephalitis, meningoencephalitis, peripheral neuropathies and deaths among newborns (mother-to-child infection), infants and elderly patients.

Arbovirus infections of the nervous system: Current trends and future threats

Arthropod-borne viruses (arboviruses) are among the most serious international infectious threats to the human nervous system and neurologic diseases that may be transmitted by arthropods to humans include meningitis, encephalitis, myelitis, and encephalomyelitis.

Fulminant Herpes Simplex Virus Type I Encephalitis Despite Maximal Medical Therapy

The case of a 19-year-old female with HSE who received standard acyclovir therapy and subsequently required multiple antiviral therapeutics and steroid therapy is discussed.

Molecular Methods for Diagnosis of Viral Encephalitis

This review discusses general principles of PCR and reverse transcription-PCR, including qualitative, quantitative, and multiplex techniques, with comment on issues of sensitivity, specificity, and positive and negative predictive values.
...

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