Viral cultures for COVID-19 infectivity assessment. Systematic review

@article{Jefferson2020ViralCF,
  title={Viral cultures for COVID-19 infectivity assessment. Systematic review},
  author={Tom Jefferson and Elizabeth A. Spencer and Jon Brassey and Carl J. Heneghan},
  journal={medRxiv},
  year={2020}
}
We report the results of a review of the evidence from studies comparing SARS-CoV-2 culture with reverse transcriptase polymerase chain reaction (rt-PCR), as viral culture represents the best indicator of current infection and infectiousness of the isolate. We identified fourteen studies succeeding in culturing or observing tissue invasion by SARS-CoV in sputum, naso or oropharyngeal, urine, stool and environmental samples from patients diagnosed with Covid-19. The data are suggestive of a… Expand
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