Viral channel-forming proteins.

  title={Viral channel-forming proteins.},
  author={Wolfgang B. Fischer and Jens Kr{\"u}ger},
  journal={International review of cell and molecular biology},
Channel-forming proteins are found in a number of viral genomes. In some cases, their role in the viral life cycle is well understood, in some cases it needs still to be elucidated. A common theme is that their mode of action involves a change of electrochemical or proton gradient across the lipid membrane which modulates the viral or cellular activity. Blocking these proteins can be a suitable therapeutic strategy as for some viruses this may be "lethal." Besides the many biological relevant… CONTINUE READING

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