Viral carcinogenesis in skin cancer.

  title={Viral carcinogenesis in skin cancer.},
  author={V. Molho-Pessach and M. Lotem},
  journal={Current problems in dermatology},
  • V. Molho-Pessach, M. Lotem
  • Published 2007
  • Biology, Medicine
  • Current problems in dermatology
  • The skin is an organ in which direct contact with viruses, solar UV irradiation and increased susceptibility to immune suppression gather to support viral tumorigenesis. Viruses transform keratinocytes by activation of cancer-promoting genes. Viral proteins may directly act as oncogenes that drive cells to proliferate or generate inflammatory responses and cause regeneration of injured cells that eventually lead to malignant transformation. Accelerated viral carcinogenesis is observed in the… CONTINUE READING
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