Viral RNA modulates the acid sensitivity of foot-and-mouth disease virus capsids.

@article{Curry1995ViralRM,
  title={Viral RNA modulates the acid sensitivity of foot-and-mouth disease virus capsids.},
  author={S. K. Curry and Charles C. Abrams and Elizabeth Fry and John C. Crowther and Graham J Belsham and David I Stuart and Andrew Malcolm King},
  journal={Journal of virology},
  year={1995},
  volume={69 1},
  pages={430-8}
}
Foot-and-mouth disease virus (FMDV) manifests an extreme sensitivity to acid, which is thought to be important for entry of the RNA genome into the cell. We have compared the low-pH-induced disassembly in vitro of virions and natural empty capsids of three subtypes of serotype A FMDV by enzyme-linked immunosorbent assay and sucrose gradient sedimentation… CONTINUE READING