Viral IL-6 blocks neutrophil infiltration during acute inflammation.


Pathologies arising as a consequence of human herpesvirus-8 (HHV8) infections are closely associated with the autocrine activity of a HHV8 encoded IL-6 (vIL-6), which promotes proliferation of infected cells and their resistance to apoptosis. In this present report, studies show that vIL-6 may also be important in influencing the host's immunological… (More)


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@article{Fielding2005ViralIB, title={Viral IL-6 blocks neutrophil infiltration during acute inflammation.}, author={Ceri A Fielding and Rachel M McLoughlin and Chantal S Colmont and Marina Kovaleva and Dean A Harris and Stefan Rose-John and Nicholas Topley and Simon A Jones}, journal={Journal of immunology}, year={2005}, volume={175 6}, pages={4024-9} }