Violation of the ISNT rule in Nonglaucomatous pediatric optic disc cupping.

@article{Pogrebniak2010ViolationOT,
  title={Violation of the ISNT rule in Nonglaucomatous pediatric optic disc cupping.},
  author={Alexander E. Pogrebniak and Ben Wehrung and Katherine L. Pogrebniak and Rajesh K. Shetty and Pam Crawford},
  journal={Investigative ophthalmology \& visual science},
  year={2010},
  volume={51 2},
  pages={
          890-5
        }
}
PURPOSE To determine whether nonglaucomatous optic disc cupping in children violates the ISNT rule (which states that for normal optic discs the neuroretinal rim width is greatest in the order inferior >or= superior >or= nasal >or= temporal). METHODS Digital ocular fundus photographs from a random cohort of children with large optic disc cups of nonglaucomatous origin were analyzed in masked fashion by using computer graphic software. The diameter and perimeter of each optic disc and optic… 

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TLDR
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Application of the ISNT Rule to Neuroretinal Rim Thickness Determined Using Cirrus HD Optical Coherence Tomography
TLDR
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TLDR
The cup was absent in 15% of the assessed eyes, and the inferior was the most common quadrant with the thickest neuroretinal rim and the temporal, the thinnest, in eyes violating the ISNT rule.
The “ISN'T Rule” in Healthy Participant Optic Nerve Head by Confocal Scanning Laser Ophthalmoscopy
TLDR
In healthy participants the rim shape as measured by the HRT did not follow the ISN'T rule, except that the smallest rim part was located in the temporal disc region, and the thickness of the rim was similar in the superior and the inferior sectors by HRT.
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