Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation.

@article{Ness1994VintageRA,
  title={Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation.},
  author={Scott A Ness and James Douglas Engel},
  journal={Current opinion in genetics & development},
  year={1994},
  volume={4 5},
  pages={718-24}
}
Pluripotent hematopoietic stem cells can differentiate into a number of distinct specialized cell types; however, no single lineage-specific master regulators have been identified that can activate individual patterns of gene expression. Recent evidence suggests that such lineage determination is regulated by a combinatorial matrix of regulatory proteins… CONTINUE READING