Vinpocetine regulates cation channel permeability of inner retinal neurons in the ischaemic retina

@article{NivisonSmith2014VinpocetineRC,
  title={Vinpocetine regulates cation channel permeability of inner retinal neurons in the ischaemic retina},
  author={Lisa Nivison-Smith and Monica L. Acosta and Stuti L. Misra and Brendan J. O'Brien and Michael Kalloniatis},
  journal={Neurochemistry International},
  year={2014},
  volume={66},
  pages={1-14}
}
Vinpocetine is a natural drug which exerts neuroprotective effects in ischaemia of the brain through actions on cation channels, glutamate receptors and other pathways. This study investigated the effect of vinpocetine on cation channel permeability of inner retinal neurons after acute retinal metabolic insult. We focused on amacrine and ganglion cells immunoreactive for calretinin or parvalbumin due to their previously documented susceptibility to ischaemia. Using the probe, 1-amino-4… Expand
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