Vimentin Regulates Invasiveness and Is a Poor Prognostic Marker in Non-small Cell Lung Cancer.

@article{Tadokoro2016VimentinRI,
  title={Vimentin Regulates Invasiveness and Is a Poor Prognostic Marker in Non-small Cell Lung Cancer.},
  author={Akira Tadokoro and Nobuhiro Kanaji and Dage Liu and Hiroyasu Yokomise and Reiji Haba and Tomoya Ishii and Takehiro Takagi and Naoki Watanabe and Nobuyuki Kita and Norimitsu Kadowaki and Shuji Bandoh},
  journal={Anticancer research},
  year={2016},
  volume={36 4},
  pages={1545-51}
}
BACKGROUND Lung cancer cells often express vimentin. However, the function of vimentin in lung cancer cells has not been fully evaluated. MATERIALS AND METHODS We evaluated the association between vimentin expression in resected non-small cell lung cancer (NSCLC) specimens and prognosis. Short-interfering RNA targeting vimentin and establishment of an invasive cell line by repeated selection of invasive cells using a Matrigel membrane invasion chamber system (MICS) were performed. MICS was… CONTINUE READING
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