Villus epithelial injury induced by infection with the nematode Nippostrongylus brasiliensis is associated with upregulation of granzyme B.

@article{Fujiwara2004VillusEI,
  title={Villus epithelial injury induced by infection with the nematode Nippostrongylus brasiliensis is associated with upregulation of granzyme B.},
  author={Atsushi Fujiwara and Yuichi Kawai and Shuji Sekikawa and Takahiro Horii and Minoru Yamada and Shoji Mitsufuji and Naoki Arizono},
  journal={The Journal of parasitology},
  year={2004},
  volume={90 5},
  pages={1019-26}
}
Intestinal parasite infections induce thymus-dependent villus atrophy, but the effector mechanisms directly responsible for the development of villus atrophy are not thoroughly understood. In this study, we analyzed the expression of cytotoxic factors or ligands in athymic nude rnu/rnu rats and their littermate euthymic rnu/+ rats infected with the nematode… CONTINUE READING