Vigorous exercise increases brain lactate and Glx (glutamate<ce:hsp sp=0.12></ce:hsp>+<ce:hsp sp=0.12></ce:hsp>glutamine): A dynamic 1H-MRS study

@article{Maddock2011VigorousEI,
  title={Vigorous exercise increases brain lactate and Glx (glutamate<ce:hsp sp=0.12></ce:hsp>+<ce:hsp sp=0.12></ce:hsp>glutamine): A dynamic 1H-MRS study},
  author={Richard J. Maddock and Gretchen A. Casazza and Michael H. Buonocore and Costin Tanase},
  journal={NeuroImage},
  year={2011},
  volume={57},
  pages={1324-1330}
}
Vigorous exercise increases lactate and glucose uptake by the brain in excess of the increase in brain oxygen uptake. The metabolic fate of this non-oxidized carbohydrate entering the brain is poorly understood, but accumulation of lactate in the brain and/or increased net synthesis of amino acid neurotransmitters are possible explanations. Previous proton magnetic resonance spectroscopy (1H-MRS) studies using conventional pulse sequences have not detected changes in brain lactate following… CONTINUE READING

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