View of the regulatory use of rat liver foci data in the Federal Republic of Germany.

Abstract

Altered hepatocellular foci (AHF) are suspected of being phenotypic markers of a stage in the sequential process of tumor development in the liver. A number of short-term and mid-term tests, including some that use AHF as an endpoint, have been reviewed by the Federal Health Office to determine if they are suitable to replace long-term animal experiments… (More)

Topics

Cite this paper

@article{RichterReichhelm1989ViewOT, title={View of the regulatory use of rat liver foci data in the Federal Republic of Germany.}, author={H.-B. Richter-Reichhelm}, journal={Toxicologic pathology}, year={1989}, volume={17 4 Pt 1}, pages={721-3} }