Vicinal Difluoroalkylation and Aminosulfonylation of Alkynes under Photoinduced Conditions.

@article{Xiang2017VicinalDA,
  title={Vicinal Difluoroalkylation and Aminosulfonylation of Alkynes under Photoinduced Conditions.},
  author={Yuanchao Xiang and Yuewen Li and Yunyan Kuang and Jie Wu},
  journal={Chemistry},
  year={2017},
  volume={23 5},
  pages={1032-1035}
}
A photoinduced vicinal difluoroalkylation and aminosulfonylation of alkynes under photocatalysis was realized. The combination of ethyl 2-bromo-2,2-difluoroacetate, alkynes, and DABCO⋅(SO2 )2 with hydrazines, catalyzed by 9-mes-10-methyl acridinium perchlorate in the presence of visible light, afforded (E)-ethyl 2,2-difluoro-4-aryl-4-sulfamoylbut-3-enoates in good yields with high stereoselectivity. This four-component reaction proceeds through radical addition with the insertion of sulfur… CONTINUE READING