Viburspiran, an Antifungal Member of the Octadride Class of Maleic Anhydride Natural Products†

  title={Viburspiran, an Antifungal Member of the Octadride Class of Maleic Anhydride Natural Products†},
  author={Muhammad Saleem and Hidayat Hussain and Ishtiaq Ahmed and Siegfried Draeger and Barbara Joan Schulz and Kathrin Meier and Michael Steinert and Gennaro Pescitelli and Tibor Kurt{\'a}n and Ulrich Fl{\"o}rke and Karsten Krohn},
  journal={European Journal of Organic Chemistry},
Viburspiran (8), a structurally new member of the maleic anhydride natural products, was isolated, along with seven known compounds 9–15, from the fungal endophyte Cryptosporiopsis sp. The structure of the new compound was elucidated by spectroscopic methods and confirmed by single-crystal X-ray analysis. The absolute configuration was established by TDDFT CD calculations by using the solid-state structure for input geometry. Viburspiran (8) is the first representative of a new class of eight… Expand
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