Vibrio parahaemolyticus thermostable direct hemolysin modulates cytoskeletal organization and calcium homeostasis in intestinal cultured cells.

@article{Fabbri1999VibrioPT,
  title={Vibrio parahaemolyticus thermostable direct hemolysin modulates cytoskeletal organization and calcium homeostasis in intestinal cultured cells.},
  author={Alessia Fabbri and Loredana Falzano and Claudio Frank and Gianfranco Donelli and P. Matarrese and Francesco Maria Raimondi and Alessio Fasano and Carla Fiorentini},
  journal={Infection and immunity},
  year={1999},
  volume={67 3},
  pages={1139-48}
}
Vibrio parahaemolyticus is a marine bacterium known to be the leading cause of seafood gastroenteritis worldwide. A 46-kDa homodimer protein secreted by this microorganism, the thermostable direct hemolysin (TDH), is considered a major virulence factor involved in bacterial pathogenesis since a high percentage of strains of clinical origin are positive for TDH production. TDH is a pore-forming toxin, and its most extensively studied effect is the ability to cause hemolysis of erythrocytes from… CONTINUE READING

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