Vibrio alginolyticus, a tetrodotoxin-producing bacterium, in the intestines of the fish Fugu vermicularis vermicularis

  title={Vibrio alginolyticus, a tetrodotoxin-producing bacterium, in the intestines of the fish Fugu vermicularis vermicularis},
  author={Tamao Noguchi and Deng Fwu Hwang and Osamu Arakawa and H. Sugita and Yoshiaki Deguchi and Yosuke Shida and K. Hashimoto},
  journal={Marine Biology},
To clarify the mechanism of toxification in animals contaminated with tetrodotoxin, the intestinal contents of the puffer Fugu vermicularis vermicularis were examined for bacterial flora in 1985. Twenty-six out of 33 strains belonged to the genus Vibrio. These bacteria were classified into Groups I to VII, based on biological and biochemical characters. High performance liquid chromatography and gas chromatography-mass spectrometry, together with mouse bioassay for toxicity, clearly… 

Microflora and tetrodotoxin-producing bacteria in a gastropod, Niotha clathrata.

  • C. A. ChengD. Hwang K. Hasimoto
  • Environmental Science
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1995

Two novel species of tetrodotoxin-producing bacteria isolated from toxic marine puffer fishes.

Microflora and Tetrodotoxin-producing Bacteria in the Lined Moon Shell Natica lineata.

The lined moon shell Natica lineata was seasonally collected from two places in Taiwan, Kaohsiung City, and Pintgung Prefecture, and assayed for anatomical distribution of tetrodotoxin (TTX) and

Isolation and Identification of a New Tetrodotoxin-Producing Bacterial Species, Raoultella terrigena, from Hong Kong Marine Puffer Fish Takifugu niphobles

The results reiterate that the TTX found in puffer fish was likely produced by the associated bacteria and TTX are widely produced amongst a diversity of bacterial species.

Effect of Bacteriophages on Vibrio alginolyticus Infection in the Sea Cucumber, Apostichopus japonicus (Selenka)

A two-phage mixture which may have potential for use as an antibacterial agent to prevent V. alginolyticus infection in the sea cucumber is described.

Tissue distribution of tetrodotoxin and its analogs in Lagocephalus pufferfish collected in Vietnam

The extract from muscle of L. spadiceus muscle was regarded to be non-toxic as far as samples collected in the present study are concerned, and the presence of a high amount of 5,6,11-trideoxyTTX (TDT), but no TTX was revealed.

Production of Bioactive Secondary Metabolites by Marine Vibrionaceae

This account underlines the pending potential for exploring new bacterial sources of bioactive compounds and the challenges related to their investigation, and highlights some of the most interesting structures from this group of bacteria.

No Evidence for a Culturable Bacterial Tetrodotoxin Producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida)

No C9 base or TTX was detected in isolates or broth experiments (past day 0), suggesting a culturable microbial source of TTX in P. maculata and Stylochoplana sp.

Tetrodotoxin-Producing Bacteria: Detection, Distribution and Migration of the Toxin in Aquatic Systems

This review is devoted to the marine bacterial producers of tetrodotoxin (TTX), a potent non-protein neuroparalytic toxin, and examines issues relating to toxin migration from bacteria to TTX-bearing animals.



Occurrence of tetrodotoxin in the Japanese ivory shell Babylonia japonica.

Specimens of the Japanese ivory shell Babylonia japonica from Sakajiri Bay, Fukui Prefecture, were all found to be toxic throughout the survey period, Aug. to Nov. 1980; the maximum toxicity (as

Occurrence of tetrodotoxin and anhydrotetrodotoxin in Vibrio sp. isolated from the intestines of a xanthid crab, Atergatis floridus.

Results showed the production of TTX and anhydroTTX in the Vibrio sp.

トゲモミジガイ(ヒトデ)から分離したVibrio alginolyticusによるテトロドトキシンの産生

Intestines of a starfish Astropecten polyacanthus were examined for microflora, it was concluded that these strains, especially the two V. alginolyticus strains, could closely be involved in toxification of the starfish.

Tetrodotoxin as a biological defense agent for puffers [Fugu niphobles, F. vermicularis vermicularis and F. pardalis]

From these and other results, it was strongly suggested that TTX acts as a biological defense agent in puffers.

Occurrence of paralytic toxicity in marine flatworms.

Some seasonal variation in toxicity was recognized in this type of flatworm, and most of the “type B” specimens were found to be nontoxic, except for some specimens which showed a toxicity up to 914 MU/g whole body.

External secretion of tetrodotoxin from puffer fishes stimulated by electric shock

Four toxic species of puffers secreted large amounts of tetrodotoxin into the surrounding water immediately after being stimulated by electric shock, and this is generally accepted as a repelling behavior of these species.

Occurrence of tetrodotoxin in the flatworm Planocera multitentaculata.

Bacterial Production of Tetrodotoxin and Anhydrotetrodotoxin

Recherche de l'origine veritable de la toxine marine tetrodotoxine produite par une bacterie Pseudomonas sp. provenant de l'algue Jania sp.

Manual of clinical microbiology

A collaborative team of editors and authors from around the world revised the Manual to include the latest applications of genomics and proteomics, producing an authoritative work of two volumes filled with current findings regarding infectious agents, leading-edge diagnostic methods, laboratory practices, and safety guidelines.

Manual of methods for general bacteriology.

Reading everything good is the choice of getting new inspirations, religion, sciences, politics, social, literature, and fictions will enrich you for not only one aspect.