Vibrational dynamics of icosahedrally symmetric biomolecular assemblies compared with predictions based on continuum elasticity.

@article{Yang2009VibrationalDO,
  title={Vibrational dynamics of icosahedrally symmetric biomolecular assemblies compared with predictions based on continuum elasticity.},
  author={Zheng Yang and Ivet Bahar and Michael Widom},
  journal={Biophysical journal},
  year={2009},
  volume={96 11},
  pages={4438-48}
}
Coarse-grained elastic network models elucidate the fluctuation dynamics of proteins around their native conformations. Low-frequency collective motions derived by simplified normal mode analysis are usually involved in biological function, and these motions often possess noteworthy symmetries related to the overall shape of the molecule. Here, insights into these motions and their frequencies are sought by considering continuum models with appropriate symmetry and boundary conditions to… CONTINUE READING

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