Vibrational Sum-Frequency Scattering for Detailed Studies of Collagen Fibers in Aqueous Environments

Abstract

Protein fibers play a crucial role in many disease related phenomena and biological systems. A structural analysis of fibrous proteins often requires labeling approaches or disruptive sample preparation while it lacks chemical specificity. Here we demonstrate that the technique of vibrational sum-frequency scattering (SFS) provides a label-free pathway for… (More)
DOI: 10.1021/ja508190d

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