Viable offspring derived from fetal and adult mammalian cells

@article{Wilmut1997ViableOD,
  title={Viable offspring derived from fetal and adult mammalian cells},
  author={Ian Wilmut and A. E. Schnieke and Jim Mcwhir and A. J. Kind and K. Campbell},
  journal={Nature},
  year={1997},
  volume={385},
  pages={810-813}
}
  • Ian Wilmut, A. E. Schnieke, +2 authors K. Campbell
  • Published 1997
  • Biology, Medicine
  • Nature
  • Fertilization of mammalian eggs is followed by successive cell divisions and progressive differentiation, first into the early embryo and subsequently into all of the cell types that make up the adult animal. Transfer of a single nucleus at a specific stage of development, to an enucleated unfertilized egg, provided an opportunity to investigate whether cellular differentiation to that stage involved irreversible genetic modification. The first offspring to develop from a differentiated cell… CONTINUE READING

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