Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection

@article{Thulin2006ViableGA,
  title={Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection},
  author={Pontus Thulin and Linda Johansson and Donald Edward Low and Bing Siang Gan and Malak Kotb and Allison Mcgeer and Anna Norrby-Teglund},
  journal={PLoS Medicine},
  year={2006},
  volume={3},
  pages={18 - 24}
}
BACKGROUND Group A streptococcal severe soft tissue infections, such as necrotizing fasciitis, are rapidly progressive infections associated with high mortality. Group A streptococcus is typically considered an extracellular pathogen, but has been shown to reside intracellularly in host cells. METHODS AND FINDINGS We characterized in vivo interactions between group A streptococci (GAS) and cells involved in innate immune responses, using human biopsies (n = 70) collected from 17 patients with… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 46 references

Cytolysin-dependent evasion of lysosomal killing.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 2 Excerpts

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