Vestiges of a DNA methylation system in Drosophila melanogaster?

  title={Vestiges of a DNA methylation system in Drosophila melanogaster?},
  author={Susan Tweedie and Huck-Hui Ng and Andrew L. Barlow and Bryan M. Turner and Brian Hendrich and Adrian Bird},
  journal={Nature Genetics},
The insect Drosophila melanogaster belongs to an atypical group of animals with no detectable genomic 5-methylcytosine. We found, unexpectedly, that the Drosophila genome potentially encodes two proteins that resemble a cytosine DNA methyltransferase and a mammalian methyl-CpG-binding-domain (MBD) protein, respectively. The hypothetical DNA… CONTINUE READING