Vestibular and cochlear ototoxicity of topical antiseptics assessed by evoked potentials.

  title={Vestibular and cochlear ototoxicity of topical antiseptics assessed by evoked potentials.},
  author={Ronen Perez and Sharon Freeman and Haim Sohmer and Jean Yves Sichel},
  journal={The Laryngoscope},
  volume={110 9},
OBJECTIVES/HYPOTHESIS To evaluate and compare the effect of chlorhexidine gluconate, povidoneiodine, and alcohol-three antiseptics used before ear surgery-on the function of the vestibular and cochlear parts of the sand rat's inner ear. The assessment of damage is based on the recording of vestibular evoked potentials (VsEPs) and auditory brainstem response (ABR). STUDY DESIGN Prospective controlled animal study. METHODS Fat sand rats were randomly assigned to five different groups, each… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 19 extracted citations

Systematic review of ototoxic pre-surgical antiseptic preparations – what is the evidence?

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale • 2018

Chlorhexidine Keratitis: Safety of Chlorhexidine as a Facial Antiseptic.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] • 2017

Lugol's solution eradicates Staphylococcus aureus biofilm in vitro.

International journal of pediatric otorhinolaryngology • 2017
View 2 Excerpts

Ototopic applications of povidone iodine/dexamethasone in the rat.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology • 2013

Similar Papers

Loading similar papers…