Vesnarinone: a potential cytokine inhibitor.

  title={Vesnarinone: a potential cytokine inhibitor.},
  author={Shigetake Sasayama and Akira Matsumori},
  journal={Journal of cardiac failure},
  volume={2 3},
Cytokines are soluble peptides that mediate cell-to-cell interactions via specific cell surface receptors. There is a growing body of evidence that cytokines may play an important role in the pathogenesis of heart failure, and the intriguing possibility has been postulated that anticytokine therapy may favorably alter the clinical outcome of heart failure. As cytokines are essentially pleiotropic and redundant in nature, elimination of a single cytokine from the biologic system often fails to… CONTINUE READING

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