Vesicle-tethering Protein p115 by a Casein Kinase II–like Enzyme Is Required for Golgi Reassembly from Isolated Mitotic Fragments

Abstract

Coat protein I (COPI) transport vesicles can be tethered to Golgi membranes by a complex of fibrous, coiled-coil proteins comprising p115, Giantin and GM130. p115 has been postulated to act as a bridge, linking Giantin on the vesicle to GM130 on the Golgi membrane. Here we show that the acidic COOH terminus of p115 mediates binding to both GM130 and Giantin… (More)

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