Vesicle size and transmitter release at the frog neuromuscular junction when quantal acetylcholine content is increased or decreased

@article{Kloot2002VesicleSA,
  title={Vesicle size and transmitter release at the frog neuromuscular junction when quantal acetylcholine content is increased or decreased},
  author={W. Kloot and J. Molg{\'o} and R. Cameron and C. Colasante},
  journal={The Journal of Physiology},
  year={2002},
  volume={541}
}
  • W. Kloot, J. Molgó, +1 author C. Colasante
  • Published 2002
  • Chemistry, Medicine
  • The Journal of Physiology
    • We investigated whether the synaptic vesicles at the neuromuscular junction change size when their acetylcholine (ACh) content is altered. The size of the miniature endplate potential (MEPP) increased 3‐ or 4‐fold in preparations pre‐treated in a hypertonic solution in which the anion was gluconate. We measured the dimensions of synaptic vesicles in such preparations and in controls. The size of the vesicles and size distribution were indistinguishable. Quanta contained about half of the usual… CONTINUE READING
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