Vesicle pool mobilization during action potential firing at hippocampal synapses

Abstract

Using the fluorescent membrane label FM 1-43, we have measured the release, reuptake, and repriming of synaptic vesicles in response to action potential stimulation of cultured hippocampal neurons. We find that approximately 90% of a recycling vesicle pool is released during 60 s of 10 Hz action potential firing, and that a single action potential releases… (More)
DOI: 10.1016/0896-6273(95)90336-4

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@article{Ryan1995VesiclePM, title={Vesicle pool mobilization during action potential firing at hippocampal synapses}, author={Timothy A Ryan and Stephen J. Smith}, journal={Neuron}, year={1995}, volume={14}, pages={983-989} }