Vesicle fusion and formation at the surface of pinocytic vacuoles in macrophages.

  title={Vesicle fusion and formation at the surface of pinocytic vacuoles in macrophages.},
  author={James G. Hirsch and Martha E. Fedorko and Zanvil Alexander Cohn},
  journal={The Journal of cell biology},
  volume={38 3},
Pinocytic vesicles are formed in macrophages from tiny invaginations of the surface membrane. During their movement towards the centrosomal region of the cell, these pinocytic vesicles commonly fuse with one another to form vacuolar structures 0.5-1.0 in diameter. These pinocytic vacuoles soon acquire hydrolases and become secondary lysosomes; over the course of several hours, they assume the appearance of dense bodies (1,2). Several morphologic features of pinocytic vacu-oles in macrophages… CONTINUE READING


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