Vesicle dynamics in a confined Poiseuille flow: from steady state to chaos.

@article{Aouane2014VesicleDI,
  title={Vesicle dynamics in a confined Poiseuille flow: from steady state to chaos.},
  author={Othmane Aouane and Marine Thi{\'e}baud and Abdelilah Benyoussef and Christian Wagner and Chaouqi Misbah},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2014},
  volume={90 3},
  pages={
          033011
        }
}
Red blood cells (RBCs) are the major component of blood, and the flow of blood is dictated by that of RBCs. We employ vesicles, which consist of closed bilayer membranes enclosing a fluid, as a model system to study the behavior of RBCs under a confined Poiseuille flow. We extensively explore two main parameters: (i) the degree of confinement of vesicles within the channel and (ii) the flow strength. Rich and complex dynamics for vesicles are revealed, ranging from steady-state shapes (in the… 
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32 Citations

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63 References

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  • A. FarutinC. Misbah
  • Physics
    Physical review. E, Statistical, nonlinear, and soft matter physics
  • 2014
Numerically, the problem of spontaneous symmetry breaking and migration of a three-dimensional vesicle in axisymmetric Poiseuille flow is analyzed and the revealed complexity can help understanding the evolution of RBCs' in vivo circulation.

Prediction of anomalous blood viscosity in confined shear flow.

A nontrivial spatiotemporal organization of blood elements is shown to trigger hitherto unrevealed flow properties regarding the viscosity, namely ample oscillations of its normalized value as a function of hematocrit and confinement, which can contribute to the conception of new strategies to efficiently detect blood disorders via in vitro diagnosis based on confined blood rheology.
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