Very low dose naltrexone addition in opioid detoxification: a randomized, controlled trial.

@article{Mannelli2009VeryLD,
  title={Very low dose naltrexone addition in opioid detoxification: a randomized, controlled trial.},
  author={Paolo Mannelli and Ashwin A. Patkar and Kathi Peindl and David Alan Gorelick and L T Wu and Edward Gottheil},
  journal={Addiction biology},
  year={2009},
  volume={14 2},
  pages={204-13}
}
Although current treatments for opioid detoxification are not always effective, medical detoxification remains a required step before long-term interventions. The use of opioid antagonist medications to improve detoxification has produced inconsistent results. Very low dose naltrexone (VLNTX) was recently found to reduce opioid tolerance and dependence in animal and clinical studies. We decided to evaluate safety and efficacy of VLNTX adjunct to methadone in reducing withdrawal during… CONTINUE READING
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