Very high prevalence of thyroid nodules detected by high frequency (13 MHz) ultrasound examination

  title={Very high prevalence of thyroid nodules detected by high frequency (13 MHz) ultrasound examination},
  author={Sabine Guth and Ulrich Theune and Jens Aberle and A Galach and C. M. Bamberger},
  journal={European Journal of Clinical Investigation},
Background  The prevalence of thyroid nodules in a healthy population is high: in the German Papillon study, nationwide ultrasound screening of more than 90 000 people using 7·5 MHz scanners revealed the presence of thyroid nodules in 33% of the normal population. A study employing more sensitive 13 MHz scanners has not been conducted so far. 
Very high prevalence of ultrasound thyroid scan abnormalities in healthy volunteers in Modena, Italy
Thyroid US screening could allow the detection of DTC in asymptomatic subjects and this diagnosis often includes DTC at an advanced stage, thus, US screening not necessarily results in the over-diagnosis of clinically not relevant thyroid diseases.
Clinical, Cytological and Histological Correlation of Thyroid Nodule(S): An Observation Study
The increased use of carotid and other neck ultrasound coupled with the improved technology and higher resolution of ultrasound machines leads to the detection of steadily increasing numbers of asymptomatic thyroid nodules, the socalled incidentalomas.
Thyroid Nodule: Current Evaluation and Management
Experts have prompted experts to develop a more efficient and cost-effective strategy to select nodules for biopsy, treatment, and follow-up.
Thyroid nodule size calculated using ultrasound and gross pathology as predictors of cancer: A 23‐year retrospective study
This study investigated the concordance between thyroid nodule sizes measured by US and gross pathologic examination and their relationship with malignancy.
A new ultrasound nomogram for differentiating benign and malignant thyroid nodules
A new model based on TI‐RADS for evaluating ultrasound image patterns that offer improved efficacy for differentiating benign and malignant thyroid nodules is built.
Incidentally discovered thyroid nodules: frequency in an adult population during Doppler ultrasonographic evaluation of cervical vessels
It is concluded that half of the elder adult population had at least one thyroid nodule, and use of ultrasound technologies with increasing resolution seems to help significantly in detecting and also evaluating smaller and previously unknown nodules.
Evaluation of Thyroid Nodules.
Management of thyroid nodules in adults
Thyroid nodule is an abnormal growth of thyroid cells that form a lump in the thyroid gland that may be either single or multiple and the majority are asymptomatic and benign in nature.
Prevalence of thyroid incidentaloma detected by high-resolution ultrasound and their potential risk of malignancy in healthy individuals in Basrah Province
Thyroid incidentaloma is relatively common, and the majority are benign, and Ultrasound characteristics and size of nodule could be a reliable screening tool for malignant potential of the thyroid nodule.


Demonstration of nodules in the normal thyroid by echography.
An ultrasound examination was performed of the normal thyroid in 300 patients and small echoic nodules were demonstrated in 19% of the patients and fluid-filled masses in 6%.
Thyroid gland: US screening in a random adult population.
It is concluded that the prevalence of small thyroid echo abnormalities in a randomly selected adult population is rather high, a fact that supports use of a conservative approach to these types of findings.
Thyroid incidentalomas. Prevalence by palpation and ultrasonography.
The data indicate that thyroid abnormalities are very common incidental findings, emphasizing the need for a conservative approach when such lesions are encountered incidentally.
Prevalence of incidental thyroid disease in a relatively low iodine intake area.
The overall occurrence of thyroid disease is more common than suspected by clinical examination and subclinical hypothyroidism is confirmed in 27 patients with elevated serum anti-TPO autoantibodies levels.
Prevalence of thyroid disorders in the working population of Germany: ultrasonography screening in 96,278 unselected employees.
The results emphasize the importance of effective sonographic screening to detect early thyroid abnomalities in order to initiate preventive and therapeutic measures to prevent the onset or progression of disease and its sequels.
Thyroid gland: US screening in middle-aged women with no previous thyroid disease.
To determine the prevalence of thyroid nodules in the healthy population, ultrasonography (US) of the thyroid gland was performed in 101 women aged 49-58 years in an urban area in southern Finland
[Volumetric analysis of thyroid lobes by real-time ultrasound (author's transl)].
Thyroid volume as measured by real-time ultrasound in cadavers was compared with direct measurements obtained by submersion, finding the best calculated volume was obtained by multiplying with the optimised correction factor f = 0.479.
Effect of iodine intake on thyroid diseases in China.
More than adequate or excessive iodine intake may lead to hypothyroidism and autoimmune thyroiditis in cohorts from three regions with different levels of iodine intake.
Nodular goiter and goiter nodules: Where iodine deficiency falls short of explaining the facts.
  • M. Derwahl, H. Studer
  • Medicine, Biology
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • 2001
In this view, superimposed iodine shortage greatly enhances the incidence of MNG and shifts its clinical appearance toward younger ages by adding one more growth factor - presumably enhanced TSH secretion - to an intrinsically activated growth regulating network.
National Health and Nutrition Examination Survey III thyroid-stimulating hormone (TSH)-thyroperoxidase antibody relationships demonstrate that TSH upper reference limits may be skewed by occult thyroid dysfunction.
Evaluating factors influencing the TSH reference range found ethnic differences in TSH were not present when populations with the same relative frequency of thyroid antibodies were compared and TSH upper reference limits may be skewed by TPOAb-negative individuals with occult autoimmune thyroid dysfunction.