Very early combination antiretroviral therapy in infants: prospects for cure.

@article{RainwaterLovett2015VeryEC,
  title={Very early combination antiretroviral therapy in infants: prospects for cure.},
  author={Kaitlin Rainwater-Lovett and Katherine Luzuriaga and Deborah Persaud},
  journal={Current opinion in HIV and AIDS},
  year={2015},
  volume={10 1},
  pages={4-11}
}
PURPOSE OF REVIEW A single case of sustained HIV control in the absence of antiretroviral therapy or HIV-specific immune responses ensued following 18 months of combination antiretroviral therapy initiated at 30 h of age in a perinatally HIV-infected child (the Mississippi child). This case provides proof-of-concept that delay in HIV viremic rebound may ensue following very early treatment (VET) in perinatal infection, likely through marked reduction of latent replication-competent HIV… CONTINUE READING
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Age at virologic control influences peripheral blood HIV reservoir size and serostatus in perinatallyinfected adolescents

  • B Karalius
  • JAMA Pediatr
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