Very Early Changes in Olfactory Functioning Due to Alzheimer's Disease and the Role of Apolipoprotein E in Olfaction a

@article{Bacon1998VeryEC,
  title={Very Early Changes in Olfactory Functioning Due to Alzheimer's Disease and the Role of Apolipoprotein E in Olfaction a},
  author={Anna W. Bacon and Mark W. Bondi and David P. Salmon and Claire Murphy},
  journal={Annals of the New York Academy of Sciences},
  year={1998},
  volume={855}
}
ABSTRACT: Alzheimer's disease (AD) is a progressive neurodegenerative illness marked by memory loss and at least one other cognitive disturbance. Early diagnosis of the disease has proved difficult and has therefore been the focus of much research. Apolipoprotein E (ApoE), a protein manufactured and distributed throughout the body, has shown specificity of binding to the βA4 peptide, the primary component in the senile plaques of AD. Furthermore, the ApoE, epsilon 4 (ɛ4) allele, is… 

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...

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