Vertical transmission of hepatitis C virus: a tale of multiple outcomes.

  title={Vertical transmission of hepatitis C virus: a tale of multiple outcomes.},
  author={Alejandro Escobar-Guti{\'e}rrez and Hugo Soudeyns and Ariane Larouche and Juan Carlos Carpio-Pedroza and Armando Mart{\'i}nez-Guarneros and Carlos Arturo V{\'a}zquez-Chac{\'o}n and Salvador Fonseca-Coronado and Lilian H T Yamasaki and Karina Ru{\'i}z-Tovar and Mayra Cruz-Rivera},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
Globally, hepatitis C virus (HCV) infection affects approximately 130 million people and 3 million new infections occur annually. HCV is also recognized as an important cause of chronic liver disease in children. The absence of proofreading properties of the HCV RNA polymerase leads to a highly error prone replication process, allowing HCV to escape host immune response. The adaptive nature of HCV evolution dictates the outcome of the disease in many ways. Here, we investigated the molecular… Expand
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  • Biology, Medicine
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  • 2001
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