Vertical transmission of Trypanosoma cruzi infection: quantification of parasite burden in mothers and their children by parasite DNA amplification.

@article{Bua2012VerticalTO,
  title={Vertical transmission of Trypanosoma cruzi infection: quantification of parasite burden in mothers and their children by parasite DNA amplification.},
  author={Jacqueline Bua and Bibiana J Volta and Elsa Beatriz Vel{\'a}zquez and Andr{\'e}s Mariano Ruiz and Ana Mar{\'i}a De Rissio and Rita L. Cardoni},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={2012},
  volume={106 10},
  pages={623-8}
}
The relationship between parasite burden and vertical transmission of Trypanosoma cruzi was studied in pairs of chronically infected women and their children in a non-endemic area. Parasitemia was quantified by quantitative polymerase chain reaction (qPCR) in the peripheral blood amplifying a nuclear T. cruzi DNA and expressed as equivalent amounts of CL Brener parasites DNA per ml (eP/ml). Similar levels of parasitemia were found in non-transmitting pregnant women and in non-pregnant women: 1… CONTINUE READING
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